Facile one-pot four-component synthesis of 3,4-dihydro-2-pyridone derivatives: Novel urease inhibitor scaffold
نویسندگان
چکیده
منابع مشابه
A facile one-pot four-component synthesis of dihydropyrrol-2-ones using Cl3CCO2H
A convenient synthesis of different types of polyfunctional dihydropyrrol-2-ones via one-pot four component reactions of formaldehyde, dialkyl acetylenedicarboxylates and amines, catalyzed by trichloroacetic acid (Cl3CCO2H) at room temperature has been investigated. The significant advantages of this synthetic method are mild reaction conditions, available and inexpensive material, short reacti...
متن کاملA facile one-pot four-component synthesis of dihydropyrrol-2-ones using Cl3CCO2H
A convenient synthesis of different types of polyfunctional dihydropyrrol-2-ones via one-pot four component reactions of formaldehyde, dialkyl acetylenedicarboxylates and amines, catalyzed by trichloroacetic acid (Cl3CCO2H) at room temperature has been investigated. The significant advantages of this synthetic method are mild reaction conditions, available and inexpensive material, short reacti...
متن کاملFour-Component, One-Pot Synthesis of Novel Conjugated Indole-Imidazole Derivatives
A series of new tetrasubstituted imidazoles 2-phenyl-3-(1, 4, 5-triphenyl-1H-imidazol-2-yl)-1H-indole derivatives substituted with –F, Cl, Br, I,-OCH3 and -NHCOCH3 were synthesized using a multicomponent reaction. The compounds were obtained in good yields by easy workup and with high purity
متن کاملa facile one-pot four-component synthesis of dihydropyrrol-2-ones using cl3cco2h
a convenient synthesis of different types of polyfunctional dihydropyrrol-2-ones via one-pot four component reactions of formaldehyde, dialkyl acetylenedicarboxylates and amines, catalyzed by trichloroacetic acid (cl3cco2h) at room temperature has been investigated. the significant advantages of this synthetic method are mild reaction conditions, available and inexpensive material, short reacti...
متن کاملUltrasound-promoted one-pot, four-component synthesis of pyridin-2(1H)-one derivatives.
An efficient one-pot synthesis of 1,6-diamino-2-oxo-1,2,3,4-tetrahydro- pyridine-3,5-dicarbonitrile derivatives by four-component piperidine-catalyzed reactions of a ketone, malononitrile, ethyl cyanoacetate and hydrazine hydrate under ultrasound irradiation is described. This method provides several advantages such as shorter reaction times, excellent yields, and a simple workup procedure.
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Research in Pharmaceutical Sciences
سال: 2017
ISSN: 1735-5362
DOI: 10.4103/1735-5362.213980